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Table 2 Data abstracted from studies regarding developmental defects of enamel in People with Cystic Fibrosis

From: The prevalence of developmental defects of enamel in people with cystic fibrosis: a systematic review

Author

DDE Status

Conclusion

Jagels&Sweeney 1976

Case 5%

Control 1%

There is no significant difference in the percentage of subjects with DDE between the case and control groups.

Primosch 1980

Case 33%

Control 13–15%

There was a higher incidence of DDE in the case group when compared to the control group.

Narang 2003

Case 10% (primary teeth)

41% (permanent teeth)

Control 11% (primary teeth)

21% (permanent teeth)

Higher % of opacities in incisor and molar teeth in the case group compared to the control group.

Azevedo 2006

Case 39% (demarcated opacity)

15% (diffuse opacity)

3% (hypoplasia)

Control 11% (demarcated opacity)

17% (diffuse opacity)

2% (hypoplasia)

Higher prevalence of demarcated and hypoplastic DDE in the case group compared to the control group.

Ferrazzano 2009

Case 55.6%

Control 22%

A statistically significant higher prevalence of DDE in the case group.

Ferrazzano 2012

Case 33% (primary teeth)

56% (permanent teeth)

Control 20% (primary teeth)

23% (permanent teeth)

There is a higher prevalence of DDE in the case group.

Peker 2014

Case 83.3% (mild)

16.7% (moderate)

0% (severe)

Control 100% (mild)

0% (moderate)

0% (severe)

Higher prevalence of DDE in the case group.

Collard 2016

Case 15%

A similar proportion of enamel defects in the case group when compared to the national Welsh average.

Abu-Zahra 2019

Case 50% (permanent teeth)

60% (first permanent molars and

Incisors)

Higher prevalence of DDE in the case group compared to national averages.

Pawlaczyk-Kamieńska 2019

Case 54.55%

Control 22.73%

Higher prevalence of DDE in the case group.