Fig. 7From: Inhibition of ZDHHC16 promoted osteogenic differentiation and reduced ferroptosis of dental pulp stem cells by CREBCREB regulated the effects of ZDHHC16 on Ferroptosis of DPSCsCREB agonist promoted GSH activity levels (A), reduced iron concentration (B) and LDH activity levels (C), inhibited PI-positive cells (D), increased MPT (E) and JC-1 disaggregation (F) of DPSCs by ZDHHC16 up-regulation; CREB inhibitor reduced GSH activity levels (G), increased iron concentration (H) and LDH activity level (I), promoted PI-positive cells (J), and suppressed MPT (K) and JC-1 disaggregation (L) of DPSC by ZDHHC16 down-regulation.**p < 0.01 compared with negative or si-nc, ##p < 0.01 compared with ZDHHC16 or si-ZDHHC16.Back to article page