Table 2 Comparison of salivary TNF-α, IL-6, IL-1β, and IFN-γ levels between type-2 diabetic patients and control individuals at baseline, 2 hours after tooth extraction and 48 hours after tooth extraction
No. | Marker | group | number | Baseline levels | 2 hours after extraction | 48 hours after extraction | |||
|---|---|---|---|---|---|---|---|---|---|
Mean ± SD pg/ml | P value | Mean ± SD pg/ml | P value | Mean ± SD pg/ml | P value | ||||
1 | TNF-α alpha | Diabetes mellitus | 20 | 29.42 ± 20.903 | .335 | 19.83 ± 11.761 | .020* | 35.46 ± 31.435 | .075 |
Control | 7 | 39.57 ± 16.387 | 47.82 ± 38.108 | 37.52 ± 14.424 | |||||
2 | IL-6 | Diabetes mellitus | 20 | 101.96 ± 172.645 | .740 | 239.49 ± 412.353 | .678 | 416.76 ± 618.496 | .010** |
Control | 7 | 91.73 ± 133.547 | 375.62 ± 431.612 | 141.09 ± 100.244 | |||||
1.3 | IL-1β | Diabetes mellitus | 20 | 1481.91 ± 1450.406 | .016* | 991.29 ± 683.816 | .046* | 2166.88 ± 2126.603 | .261 |
Control | 7 | 4418.61 ± 5004.515 | 1804.47 ± 1834.959 | 2460.50 ± 1285.304 | |||||
4 | IFN-γ | Diabetes mellitus | 20 | 65.17 ± 36.501 | .135 | 55.71 ± 30.514 | .463 | 70.30 ± 43.867 | .084 |
Control | 7 | 88.66 ± 26.147 | 78.20 ± 27.253 | 73.62 ± 29.802 | |||||