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Fig. 4 | BMC Oral Health

Fig. 4

From: Anti-angiogenic drug aggravates the degree of anti-resorptive drug-based medication-related osteonecrosis of the jaw by impairing the proliferation and migration function of gingival fibroblasts

Fig. 4

Anti-angiogenic drugs significantly inhibit the clonogenic and proliferative abilities of gingival fibroblasts than anti-resorptive drugs. A Crystal violet staining and 40 × microscope observation of 6-well plates with gingival fibroblasts seeded to observe the colony formation ability. B Statistical analysis of colony formation numbers of gingival fibroblasts post different drug treatments. C Statistical analysis of gingival fibroblasts post different drug treatments using CCK-8 assay. ANOVA was performed. *P < 0.05; **P < 0.01. Scale bars in A (left panel),1 mm; A (right panel), 100 µm

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BMC Oral Health

ISSN: 1472-6831

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