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Fig. 3 | BMC Oral Health

Fig. 3

From: Anti-angiogenic drug aggravates the degree of anti-resorptive drug-based medication-related osteonecrosis of the jaw by impairing the proliferation and migration function of gingival fibroblasts

Fig. 3

Combined use of anti-resorptive and anti-angiogenic drugs interferes with both soft tissue coverage of extraction sockets and new bone formation in extraction sockets. A Masson staining to observe the results of soft tissue coverage and new bone formation in the extraction socket of the left maxillary second molar. The inset shows the boxed region magnified. B Statistical analysis of empty bone lacuna in extraction socket post different drug treatments. Yellow arrows indicate the formation of a normal mucosal coverage. Red arrows indicate empty bone lacuna. Scale bar in A, 100 μm

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BMC Oral Health

ISSN: 1472-6831

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