Fig. 1
From: A rare case of pemphigus vulgaris disguised as a malignant gingival ulcer
(A) An irregular ulcer-like lesion about 2*1.5 cm in size on the palatal gingival of tooth #27. The lesion slightly protruded from the mucosal surface. (B) Cone beam CT (CBCT) showed that the buccal and palatal bone plates of tooth #27 were continuous, without bone loss. (C ~ D) Histopathological image of the ulcer on the palatal gingival of tooth #27 (H&E × 40). The pathological examination showed “chronic suppurative inflammation, ulceration with Candida albicans infection “(H&E × 100). (E) The direct immunofluorescence (DIF) assay showed positive IgG network deposition in epithelial and epidermal spinous cells. (F) The DIF assay showed that C3 is negative. (G) The image of the pemphigus vulgaris (PV) ulcer after 2 weeks of medication. (H) The image of the PV ulcer after 4 weeks of medication. (I) After 6 weeks of continuous local administration, the palatal PV ulcer was cured