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Table 1 Recommendations for the management on peri-implantitis†

From: Critical review on quality of methodology and recommendations of clinical practice guidelines for peri-implantitis

Topics

Recommendation

Supporting guidelines

Number of recommendations

Strength of recommendation#

Quality of evidence‡

Prevention

It is recognized that secondary prevention of peri-implantitis poses unique challenges that may only be partially addressed by routine supportive periodontal care programs.

EWP(2)

1

Ungraded

Ungraded

Self-performed hygiene care or professional maintenance program (e.g. proper plaque control) have positive effect on preventing peri-implant mucositis proceeding into peri-implantitis

ITI, BOA&LUHS(2), BOA&LUHS(3)

3

Ungraded

Ungraded

Caution should be used for implants in Sjögren’s Patients and diabetic patient which may have an increased risk for peri-implantitis.

EWP(1), BOA&LUHS(1)

2

Ungraded

Ungraded

Diagnosis

A diagnosis of peri-implantitis is given in the presence of mucositis in conjunction with progressive crestal bone loss

ITI

1

Ungraded

Ungraded

When clinical signs suggest the presence of peri-implantitis, the clinician is advised to take a radiograph of the site to confirm the diagnosis.

EWP(1), BOA&LUHS(3)

2

Ungraded

Ungraded

Diagnosis of peri-implantitis requires:

• Presence of bleeding and/or suppuration on gentle probing.

• Increased probing depth compared to previous examinations.

• Presence of bone loss beyond crestal bone level changes resulting from initial bone remodeling.

AAP&EFP, FDI(2)

2

Ungraded

Ungraded

In the absence of previous examination data, diagnosis of peri-implantitis can be based on the combination of:

• Presence of bleeding and/or suppuration on gentle probing.

• Probing depths of ≥ 6 mm(or ≥ 4 mm).

• Bone levels ≥ 3 mm (or ≥ 5 mm) mapical of the most coronal portion of the intraosseous part of the implant

AAP&EFP, BOA&LUHS(3)

2

Ungraded

Ungraded

Treatment

A regular maintenance program may be needed for the long-term management of peri-implantitis lesions.

ITI

1

Ungraded

Ungraded

Pretreatment phase including:

i. Thorough assessment and diagnosis

ii. Reduction of risk factors for peri-implantitis; in

particular poor oral hygiene, prostheses that prevent adequate access for plaque control, to-bacco use, presence of periodontal diseases, and systemic diseases that may predispose to peri-implant disease

ii. If required, prosthesis removal and adjustment/replacement

ITI

1

Ungraded

Ungraded

Nonsurgical debridement focused on maximal removal of biofilm, with or without antimicrobials

ITI, EAO(1)

2

Ungraded

Ungraded

The clinician should consider implant removal as a treatment option. Factors influencing this decision may include the severity of the peri-implantitis lesion, the position of the implant, the surrounding tissues, or when the treatment outcomes are likely to be unsatisfactory.

ITI, EAO(1), BOA&LUHS(3)

3

Ungraded

Ungraded

If non-surgical treatment does not resolve the

peri-implantitis lesion or arrest progressive

bone loss, surgical therapy may be considered.

EAO(1), FDI(2)

2

Ungraded

Ungraded

Proper pre- and postsurgical hygiene maintenance phases and successful implant surface decontamination are mandatory for successful surgical regenerative procedure.

Albrektsson et al., EWP(1), BOA&LUHS(2)

3

Ungraded

Ungraded

Surgical augmentative peri-implantitis therapy results in improved clinical and radiographic treatment outcomes, which is considered to be superior to non-surgical therapy in resolving peri-implantitis.

FDI(1), EAO(1), AAP(2), FDI(2), BOA&LUHS(2)

5

Ungraded

Ungraded

Surgical regenerative treatment might be chosen for intrabony defect reconstruction, whereas non-regenerative approach and implantoplasty of the supracrestal implant component is recommended.

FDI(1), BOA&LUHS(2)

2

Ungraded

Ungraded

Implant surface scaling plus antimicrobial photodynamic therapy versus implant surface scaling for the treatment of peri-implantitis is recommended compared with scaling and root planing.

AAP(1)

1

Weak

Low

Others

Monitoring

    

Regular assessment of peri-implant health is recommended during support periodontal treatment (SPT) to identify disease at an early stage.

ITI, BOA&LUHS(3)

3

Ungraded

Ungraded

The presence of purulent exudate in combination with clinically significant progressing Crestal bone loss (CBL) necessitates therapeutic intervention.

Albrektsson et al., EAO(1), EWP(1), EWP(2), AAP&EFP

5

Ungraded

Ungraded

Evaluate iatrogenic factors that might have caused the disease, including cement remnants, malpositioning of the implant, inadequate restoration-abutment seating, and overcontouring of the reconstruction that disturbs proper plaque control should be evaluated.

BOA&LUHS(3)

1

Ungraded

Ungraded

Clinical monitoring should be performed on a regular basis and supplemented by appropriate radiographic evaluation as required.

Albrektsson et al., ITI, AAP&EFP

3

Ungraded

Ungraded

Qualifications

    

Training of dental team professionals should include diagnosis and management of peri-implant disease.

ITI

1

Ungraded

Ungraded

Biomarker

    

Evidence regarding biomarkers and enzymes in peri-implant crevicular fluid (PICF) as possible predictors for peri-implantitis are very limited.

BOA&LUHS(3)

1

Ungraded

Ungraded

  1. †: The full names of the abbreviation of guidelines are as same as those in Supplementary Table 1
  2. ‡: Strength of recommendation and quality of evidence were harmonized according the composite grading system shown in Supplementary material part 2