Table 3 Multi-variable analysis of exhaled gas in the oral squamous cell carcinoma group (mean ± SD)
H2S (ng/10 ml) | p | CH3SH (ng/10 ml) | p | Total sulfur (ng/10 ml) | p | Ratio (CH3SH/H2S) | p | ||
|---|---|---|---|---|---|---|---|---|---|
Location | Tongue (n = 21) | 8.6 ± 9.6 | 0.400 | 5.4 ± 5.5 | 0.113 | 14.0 ± 13.8 | 0.224 | 1.7 ± 3.3 | 0.875 |
Gums (n = 23) | 6.8 ± 9.1 | 5.6 ± 7.8 | 12.4 ± 15.9 | 1.4 ± 2.0 | |||||
Buccal cheek (n = 6) | 12.8 ± 11.8 | 12.1 ± 9.7 | 24.9 ± 21.1 | 1.1 ± 0.6 | |||||
TNM stage | I (n = 10) | 4.2 ± 6.8 | 0.464 | 3.1 ± 3.5 | 0.897 | 7.3 ± 9.6 | 0.614 | 1.2 ± 1.1 | 0.253 |
II (n = 10) | 11.2 ± 10.7 | 10.7 ± 9.0 | 21.9 ± 17.2 | 3.0 ± 4.8 | |||||
III (n = 7) | 8.7 ± 11.3 | 6.1 ± 8.6 | 14.8 ± 19.3 | 1.8 ± 2.6 | |||||
IV (n = 23) | 8.7 ± 9.7 | 5.8 ± 6.9 | 14.4 ± 15.9 | 0.8 ± 0.7 | |||||
Surgery | No (n = 5) | 12.7 ± 11.9 | 0.288 | 8.4 ± 7.2 | 0.508 | 21.0 ± 18.4 | 0.341 | 0.9 ± 0.5 | 0.136 |
Yes (n = 45) | 7.8 ± 9.4 | 6.0 ± 7.4 | 13.8 ± 15.6 | 1.6 ± 2.6 | |||||
Chemotherapy | No (n = 40) | 6.9 ± 9.2 | 0.036 | 5.4 ± 7.2 | 0.082 | 12.2 ± 15.4 | 0.037 | 1.7 ± 2.8 | 0.050 |
Yes (n = 10) | 13.9 ± 9.5 | 9.9 ± 7.1 | 23.8 ± 14.9 | 0.7 ± 0.5 |