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Table 3 Uni- and multivariable analysis of outcomes

From: Postoperative radiotherapy may not be necessary for locally advanced head and neck squamous cell carcinoma: a case-match multicentre study

 

OS

RR (95% CI)

P

DFS

RR (95% CI)

P

Age

0.989 (0.961–1.019)

0.472

1.000 (0.974–1.027)

0.993

Gender

2.013 (0.278–14.603)

0.489

2.302 (0.318–16.664)

0.409

Smoking

0.646 (0.345–1.207)

0.171

0.784 (0.425–1.446)

0.435

Alcohol

0.828 (0.468–1.468)

0.296

0.878 (0.509–1.512)

0.638

Subsite

1.331 (1.063–1.667)

0.013

1.345 (1.084–1.669)

0.007

T stage

1.129 (0.674–1.892)

0.645

1.036 (0.632–1.701)

0.887

Lymph node

1.638 (1.164–2.305)

0.005

1.726 (1.241–2.400)

0.001

Pathological grade

1.420 (0.769–2.623)

0.263

1.700 (0.933–3.100)

0.083

Postoperation radiotherapy

1.129 (0.636–2.002)

0.679

1.158 (0.671–1.997)

0.599

Adjuvant chemotherapy

0.587 (0.283–1.215)

0.130

0.483 (0.248–0.943)

0.033

Multivariable

 Subsite

1.457 (1.122–1.890)

0.005

1.423 (1.104–1.834)

0.006

 Lymph node

1.628 (1.143–2.317)

0.007

1.725 (1.227–2.424)

0.002

 Pathological grade

1.383 (0.734–2.605)

0.316

1.590 (0.851–2.970)

0.146

 Postoperation radiotherapy

1.184 (0.649–2.162)

0.582

1.169 (0.659–2.073)

0.594

 Adjuvant chemotherapy

0.647 (0.298–1.406)

0.272

0.579 (0.283–1.186)

0.135