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Fig. 1 | BMC Oral Health

Fig. 1

From: Depletion of EREG enhances the osteo/dentinogenic differentiation ability of dental pulp stem cells via the p38 MAPK and Erk pathways in an inflammatory microenvironment

Fig. 1

Knockdown of EREG enhanced the osteo/dentinogenic differentiation ability of DPSCs. Short hairpin RNAs were used to silence the expression of EREG (EREGsh), and scramble shRNA was used as a control (Scramsh). a Western blot results for the expression of EREG in EREGsh and Scramsh DPSCs. b Real time PCR results for the expression of EREG in EREGsh and Scramsh DPSCs. cAlizarin red staining results for both groups after 2 weeks of osteogenic induction. d ALP activity results of EREGsh and Scramsh DPSCs on day 5. e Calcium quantitative analysis results for both groups after 2 weeks of osteogenic induction. f–g Real-time RT-PCR for the expression of the osteo/dentinogenic differentiation markers BSP, DMP-1 and DSPP. GAPDH was used as the internal control. Error bars represent the SD (n = 3). Student's t test was used to test statistical significance. *P ≤ 0.05. **P ≤ 0.01

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BMC Oral Health

ISSN: 1472-6831

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