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Table 4 Means of serum lipids by periodontal pathogenic burden using multivariable GLM models

From: Relationship between the burden of major periodontal bacteria and serum lipid profile in a cross-sectional Japanese study

 

Means of serum lipids

Model 1

Model 2

Model 3

MEAN ± SD

LSM

MEAN ± SD

LSM

MEAN ± SD

LSM

High-density lipoprotein (mg/dL)

 Periodontal pathogenic burden

  Low

66.2 ± 16.1

65.4

68.1 ± 14.9

66.4

68.1 ± 14.9

66.1

  Moderate

63.3 ± 16.2

63.4

63.6 ± 16.3

63.1

63.5 ± 16.3

63.0

  High

56.7 ± 13.8

56.9

56.8 ± 13.9

58.2

57.3 ± 13.8

58.9

 

P for trend > 0.05

P for trend = 0.07

P for trend = 0.05

 

Adjusted R2 = 0.10

Adjusted R2 = 0.18

Adjusted R2 = 0.19

Triglycerides (mg/dL)

 Periodontal pathogenic burden

  Low

97.1 ± 44.3

100.6

93.6 ± 44.8

100.0

93.6 ± 44.8

101.0

  Moderate

102.1 ± 51.9

101.4

101.5 ± 52.7

102.9

101.8 ± 53.1

103.7

  High

116.8 ± 75.4

116.8

117.6 ± 75.8

112.9

115.9 ± 76.1

109.6

 

P for trend > 0.05

P for trend > 0.05

P for trend > 0.05

 

Adjusted R2 = 0.05

Adjusted R2 = 0.12

Adjusted R2 = 0.14

Low-density lipoprotein (mg/dL)

 Periodontal pathogenic burden

  Low

124.1 ± 27.7

123.4

125.1 ± 29.1

123.5

125.1 ± 29.1

122.9

  Moderate

119.7 ± 29.5

119.6

119.0 ± 29.7

118.9

119.5 ± 29.8

119.3

  High

125.3 ± 26.9

125.8

125.1 ± 27.1

125.7

124.9 ± 27.6

126.0

 

P for trend > 0.05

P for trend > 0.05

P for trend > 0.05

 

Adjusted R2 = 0.14

Adjusted R2 = 0.03

Adjusted R2 = 0.03

Total Cholesterol (mg/dL)

 Periodontal pathogenic burden

 Low

209.7 ± 30.2

208.9

211.9 ± 30.6

209.9

211.9 ± 30.6

209.2

 Moderate

203.4 ± 32.8

203.2

202.8 ± 32.9

202.6

203.3 ± 32.8

203.1

 High

205.4 ± 29.2

206.1

205.5 ± 29.5

206.5

205.4 ± 30.1

206.8

 

P for trend > 0.05

P for trend > 0.05

P for trend > 0.05

 

Adjusted R2 = 0.04

Adjusted R2 = 0.03

Adjusted R2 = 0.02

  1. Model 1: Adjusted for age and gender, Model 2: Additionally adjusted for periodontitis, BMI, diabetes, and hypertension, Model 3: Additionally adjusted for smoking, drinking, exercise, tooth brushing, and dental flossing
  2. Bold indicates statistical significance (p < 0.05)