Fig. 3

Stage 3 FOD presenting with multiple periapical radiopaque lesions associated with large and multiple osteolytic areas on panoramic radiography (a) and CBCT images (b-d). Histology confirmed simple bone cysts and bony/cementoid deposits compatible with giant florid osseous dysplasia. The Schneiderian membrane thickening (white star) associated with micro-perforations of the sinus floor adjacent to the periapical radiolucent lesion of tooth 27 confirms the endodontic origin of such lesion. In contrast, the lesion on tooth 17 appears of mixed-density, is limited to the alveolar bone and respects the sinus cavity (c)