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Table 1 Clinicopathiological variables defined by gender and disease specific death (DSD)

From: Clinicopathological characteristics of oral squamous cell carcinoma in Northern Norway: a retrospective study

   

Difference

 

DSD

 
 

Men

Women

Gender

All patients

N

 
 

(n = 69)

(n = 64)

p-value*

(n = 133)

(% of total)

DSD p*

Age

      

≤50 years

8 (12%)

9 (14%)

p = 0.405

17 (13%)

4 (24%)

0.769

51-60 years

19 (28%)

11 (17%)

30 (23%)

12 (40%)

61-70 years

18 (26%)

14 (22%)

32 (24%)

14 (44%)

71-80 years

15 (22%)

15 (23%)

30 (23%)

9 (30%)

≥81 years

9 (13%)

15 (23%)

24 (18%)

8 (33%)

Tumor differentiation

     

Verrocous

1 (1%)

4 (6%)

p = 0.474

5 (4%)

0

0.142

Well

28 (41%)

28 (44%)

56 (42%)

17 (30%)

Moderate

34 (49%)

27 (42%)

61 (46%)

25 (41%)

Poor

6 (9%)

5 (8%)

11 (8%)

5 (45%)

Tumor stage

      

T1

19 (28%)

24 (39%)

p = 0.335

43 (32%)

8 (19%)

<0.001

T2

25 (36%)

21 (33%)

46 (35%)

11 (24%)

T3

4 (6%)

7 (11%)

11 (8%)

7 (64%)

T4

18 (26%)

9 (14%)

27 (20%)

17 (63%)

Unknown

3 (4%)

3 (5%)

6 (5%)

4 (67%)

Lymph node status

     

N0

42 (61%)

40 (63%)

p = 0.200

82 (62%)

21 (26%)

<0.001

N +a

21 (30%)

13 (20%)

34 (26%)

21 (62%)

Unknown

6 (9%)

11 (17%)

17 (13%)

5 (29%)

SOD b

      

Stage I

15 (22%)

17 (27%)

p = 0.316

32 (24%)

4 (13%)

<0.001

Stage II

19 (28%)

16 (25%)

35 (26%)

7 (20%)

Stage III

9 (13%)

11 (17%)

20 (15%)

10 (50%)

Stage IV

20 (29%)

10 (16%)

30 (23%)

21 (70%

Unknown

6 (9%)

10 (16%)

16 (12%)

5 (31%)

Primary site

      

Mobile tounge

34 (49%)

27 (42%)

p = 0.038

61 (46%)

18 (30%)

0.548

Floor of mouth

21 (30%)

9 (14%)

30 (22%)

12 (40%)

Alveolar rim

9 (13%)

15 (23%)

24 (18%)

8 (33%)

Buccal mucosac

4 (6%)

7 (11%)

18 (14%)

9 (50%)

Palatec

1 (1%)

3 (5%)

Otherc

0

3 (5%)

Smoking

      

Never

8 (12%)

27 (42%)

p < 0.001

35 (26%)

9 (26%)

0.566

Previous smoker

14 (20%)

6 (9%)

20 (15%)

7 (47%)

Smoker

41 (59%)

18 (28%)

59 (44%)

24 (41%)

Unknown

6 (9%)

13 (20%)

19 (14%)

7 (37%)

Alcohol consumption

     

Never

5 (7%)

23 (36%)

p < 0.001

28 (21%)

6 (21%)

0.002

< once a week

27 (39%)

20 (31%)

47 (35%)

16 (34%)

> once a week

9 (13%)

1 (2%)

10 (8%)

2 (20%)

Daily

8 (12%)

3 (5%)

11 (8%)

7 (64%)

Unknown

20 (29%)

17 (27%)

37 (28%)

16 (43%)

IRF d

      

Non-smoker/non-drinker

10 (14%)

30 (47%)

p < 0.001

40 (30%)

10 (25%)

0.120

Smoker/light drinkere

22 (32%)

13 (20%)

35 (26%)

12 (34%)

Smoker/heavy drinkere

17 (25%)

4 (6%)

21 (16%)

9 (43%)

Unknown

20 (29%)

17 (27%)

37 (28%)

16 (43%)

P16-staus f

      

Positiv

6 (10%)

4 (7%)

p = 0.625

100 (88%)

38 (33%)

0.791

Negative

54 (90%)

50 (93%)

 

10 (9%)

4 (4%)

 
  1. aincludes N1, N2a, N2b, N2c and N3.
  2. bSOD = Stage of Disease.
  3. cIn the further analyses, these three are merged.
  4. dIRF = Intergrading risk factors.
  5. elight drinker = less than once a week; heavy drinker = more than once a week or daily.
  6. fN = 114 in the p16 analysis.
  7. *p < 0.05 was regarded as statistically significant, and highlighted in boldface when present.
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