Table 3 Comparison of FD values before (T0) and after (T1) treatment and between measurement regions

ROI 1

1.462 ± 0.063

1.471 (1.410–1.509)

1.448 ± 0.064 ^a

1.450 (1.413/1.500)

0.030 ± 0.074 ^a

0.040 (-0.030/0.095)

0.382 ^Pt

ROI 2

1.418 ± 0.053

1.413 (1.392/1.447)

1.386 ± 0.089 ^b

1.392 (1.360/1.438)

-0.031 ± 0.107 ^b

-0.024 (-0.054/0.043)

0.334 ^Wr

ROI 3

1.450 ± 0.077

1.466 (1.405/1.491)

1.435 ± 0.055 ^a

1.446 (1.392/1.472)

-0.014 ± 0.094 ^b

-0.014 (-0.097/0.062)

0.450 ^Pt

ROI 4

1.443 ± 0.069

1.454 (1.399/1.503)

1.469 ± 0.064 ^a

1.472 (1.425/1.525)

0.026 ± 0.076 ^a,b

0.013 (-0.026/0.078)

0.093 ^Pt

ROI 5

1.451 ± 0.058

1.433 (1.409/1.512)

1.460 ± 0.068 ^a

1.474 (1.421–1.510)

0.010 ± 0.056 ^a,b

0.002 (-0.014/0.038)

0.379 ^Pt

P values

0.146 (F = 1.744) *

P < 0.001 (F = 6.849) *^, ***

0.030 (Chi-square = 10.674) **^, ***