Fig. 2

Autoradiograms of ¹⁴C-lidocaine in the coronary sections of maxilla. The maxilla removed at 10 and 40 min after the application of ¹⁴C-lidocaine (left) or ¹⁴C-lidocaine with epinephrine (left) was frozen, and a 10 μm frontal section was sliced at the center of the site of drug application. The blackened area shows accumulation of ¹⁴C-lidocaine. After 40 min, the blackened area increased in the maxillary section treated with lidocaine with epinephrine. In the maxillary section treated with lidocaine only, the blackened area almost disappeared