Clinical research: low-level laser therapy in accelerating orthodontic tooth movement

BMC Oral Health

Table 1 Levels of GCF cytokine concentrations in the control and laser groups during the study period

Cytokine	Day	Control group		Laser group		Difference between groups (P value)
Cytokine	Day	Mean ± SD	Change from baseline (P value)	Mean ± SD	Change from baseline (P value)	Difference between groups (P value)
IL-1β (pg/μl)	0	9.67 ± 1.63		9.581 ± 1.36		0.585
	7	11.61 ± 1.73	0.005*	12.22 ± 1.80	0.000*	0.092
	14	9.21 ± 1.19	0.482	9.69 ± 1.51	0.874	0.317
	21	9.39 ± 1.63	0.665	10.39 ± 2.07	0.260	0.001*
	28	10.60 ± 1.76	0.161	11.93 ± 1.84	0.002*	0.013*
OPG (pg/μl)	0	25.58 ± 12.36		23.63 ± 11.68		0.076
	7	12.84 ± 9.86	0.001*	6.30 ± 4.13	0.000*	0.008*
	14	12.69 ± 4.65	0.000*	11.97 ± 5.21	0.000*	0.499
	21	14.38 ± 8.99	0.002*	13.63 ± 5.63	0.001*	0.686
	28	9.58 ± 3.12	0.000*	11.36 ± 3.68	0.000*	0.066
RANKL (pg/μl)	0	2.07 ± 0.48		1.91 ± 0.19		0.207
	7	1.80 ± 0.21	0.430	2.17 ± 0.58	0.088	0.039*
	14	1.98 ± 0.34	0.833	2.20 ± 0.17	0.058	0.015*
	21	2.15 ± 0.29	0.844	2.48 ± 0.47	0.000*	0.031*
	28	1.88 ± 0.36	0.638	1.97 ± 0.17	0.710	0.253
RANKL/OPG	0	0.14 ± 0.20		0.17 ± 0.27		0.187
	7	0.23 ± 0.16	0.118	0.62 ± 0.60	0.001*	0.032*
	14	0.18 ± 0.64	0.557	0.23 ± 0.17	0.655	0.113
	21	0.20 ± 0.11	0.321	0.24 ± 0.21	0.596	0.343
	28	0.21 ± 0.07	0.203	0.19 ± 0.06	0.901	0.284

*P < 0.05 was considered significant, based on the Paired t test (for intergroup comparisons) or one-way ANOVA (for comparisons to baseline)

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