Definitive grade | Criteria |
---|---|
Grade A (high value) | Randomized clinical study or a prospective study with a well-defined control group; Clear definition of diagnosis and endpoints; Description of diagnostic reliability tests and reproducibility tests; Blinding of outcome assessment. |
Grade B (moderate value) | Cohort study or retrospective study with a well-defined control group; Clear definition of diagnosis and endpoints; Description of diagnostic reliability tests and reproducibility tests. |
Grade C (low value) | Large attrition; Unclear definition of diagnosis and endpoints; Ill-defined patient material. |