Fig. 3From: Modulation of stromal cell-derived factor 1 alpha (SDF-1α) and its receptor CXCR4 in Porphyromonas gingivalis-induced periodontal inflammationImmunohistochemical analysis of SDF-1α and CXCR4 in periodontal inflammation. Four μm thick sections of formalin-fixed, paraffin-embedded specimens were deparaffinized and immunoreactivity was detected using a DAKO ENVISION Kit. SDF-1α and CXCR4 was highly expressed in patients with periodontitis. SDF-1α and CXCR4 expression in human periodontal tissues was present predominantly in the granular and spinous layers of epithelial cells, while their expression was faint in nonperiodontitis tissues. SDF-1α and CXCR4 expression was also present in the suprabasal layer of epithelial cells. Scale bars, 50 μMBack to article page