Table 2 Etiology of recognized syndromes and associations in the entire HCAR datatset and among the subjects with OCs.
From: Oral clefts with associated anomalies: findings in the Hungarian Congenital Abnormality Registry
Etiological Entity | Entire Dataset | Subjects with OCs |
|---|---|---|
Mendelian Syndromes | ||
Stickler type I* | 4 | 2 |
Faciogenitopopliteal | 2 | 2 |
Ectrodactyly, ectodermal dysplasia, CL/P | 6 | 6 |
Diastrophic displasia | 2 | 1 |
Meckel | 28 | 4 |
Orofaciodigital type II | 5 | 5 |
Roberts | 4 | 4 |
Orofaciodigital type I | 9 | 1 |
Subtotal | 60 | 25 |
Chromosomal | ||
Trisomy 13 | 35 | 29 |
Trisomy 18 | 22 | 1 |
Deletions | 25 | 1 |
Subtotal | 82 | 31 |
Teratogenic | ||
Hydantoin | 4 | 4 |
Associations | ||
Schisis | 130 | 73 |
Total | 276 | 133 |