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Table 1 Susceptibility profile of clinically relevant oral bacteria to four antimicrobial agents

From: Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections

MIC (%)

 

CHD-FA

CHX

Organism

PMIC

MBC

SMIC

Fold change

PMIC

MBC

SMIC

Fold change

    

(SMIC/PMIC)

   

(SMIC/PMIC)

A. a *

0.25

0.25

0.5

2

0.00078

0.00313

0.025

32

S. mitis

0.0625

0.125

0.5

8

0.00078

0.00156

0.0125

16

S. mutans

0.25

0.25

0.5

2

0.00039

0.00078

0.025

64

E. faecalis

0.125

0.25

0.5

4

0.00156

0.025

0.003

2

F. nucleatum

0.125

0.5

0.5

4

0.00039

0.00078

0.195

32

P. gingivalis

0.0625

0.5

0.5

8

≤0.00039

0.00078

0.0625

≥16

  1. *A. actinomycetemcomitans.
  2. CHD-FA - (Fulhold Ltd, South Africa), CHX - (GlaxoSmithKline Consumer Health Care, UK).